Tag Archives: Postpartum

FDA Supports Intravenous Brexanolone for Postpartum Depression

In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of postpartum depression (PPD).  SAGE-547, now called brexanolone, is an allosteric modulator of GABAA receptors.  Since that time, Sage Therapeutics has conducted three randomized controlled trials, enrolling a total of 247 women diagnosed with moderate to severe postpartum depression. This… Read More »

How To Deal With Postpartum Depression

— Postpartum Depression. The phrase alone sounds scary and when you learn more about it and what it is, you realize not only is it scary but also sad. Back in the day, you used to hear people talk about having Baby Blues but that is NOT what postpartum depression. Postpartum is a real condition… Read More »

New Study at CWMH: Genetics of Postpartum Psychosis – Massachusetts General Hospital Postpartum Psychosis Project (MGHP3)

Postpartum psychosis (PPP) is a rare but serious condition, occurring in 1 to 2 per 1000 women in the weeks after delivery and associated with extreme delirium-like behavior, delusions, hallucinations, and an increased risk of suicide and infanticide.[1] While there appears to be a strong link between postpartum psychosis and bipolar disorder,[2] it is estimated… Read More »